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How Elders Can Fool Doctors and How to Help

DoctorElderlyManA frequent problem expressed among adult children is that their parents aren't truthful with their doctors. While the parent may complain at home of pain, exhibit memory problems and accuse family of theft when he or she can't locate a commonly used item, the moment the parent faces their doctor a change occurs. Like an actor on stage, the person sitting in front of the doctor becomes animated and charming. 

Read more on Agingcare about how elders can fool doctors: 

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“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

Global Alzheimer’s Study Now Enrolling


5 Tips for Maintaining Relationships with Friends when Dementia Joins the Party

Hands10While people with Alzheimer’s experience memory loss as their first symptom, people with Lewy body dementia may become easily confused. These varied symptoms can make maintaining relationships more difficult, but friendships are no less important for people with dementia than for than for the rest of us. Maintaining relationships, however, especially among friends who are not pressured to continue involvement because of a sense of duty, can take work. Caregivers can help by educating willing visitors who want to be helpful but simply don’t know how to make a visit tolerable, let alone meaningful.

Read more on HealthCentral about maintaining friendships when people have dementia:

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

Global Alzheimer’s Study Now Enrolling


Fitness and Aging Well: A Vital Correlation

BicyclingHow vital is fitness to aging well? Very. A recent study of participants in the 2015 National Senior Games, also known as the Senior Olympics, revealed that the typical participant had a fitness age of more than 20 years younger than his or her chronological age. According to the Norwegian University of Science and Technology, fitness age is determined by a measure of cardiovascular endurance and is a better predictor of longevity than chronological age. 

Read more on Healthcentral about exercise and aging well:

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

Global Alzheimer’s Study Now Enrolling


Motherhood, the Brain and Dementia: Changing Hormones Alter Risk

MotherhoodHormonesThroughout decades of study, hormone therapy (HT), often but not always the same as hormone replacement therapy (HRT), has been glorified and demonized in turn. The information that doctors receive has come from ongoing studies that seemed to offer over time radically conflicting results. A new study may add more confusion since this study has found that not only does HT given near menopause create changes in a woman’s brain, but motherhood itself creates changes. 

Read full article on HealthCentral about motherhood and brain health:

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

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Caring for Parents Who Weren’t So Caring

Aging in Place or Assisted Living: It’s About Choices

GrandmotherDaughterAccording to an AARP survey, the vast majority of boomers have stated that they want to stay in their current homes rather than move to another setting for their later years. This attitude has been the springboard for many aging in place advocates as well as businesses like contractors and high tech companies.  It’s not hard to understand why 60-year-olds would say that they want to remain in their home for life rather than move to assisted living or a nursing home. These are generally people who are relatively healthy and feel that they can hire help for whatever they need down the road. 

Read more on HealthCentral about living choices as we age:

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

Global Alzheimer’s Study Now Enrolling


When Addressing Elders begin with Respectful Formality

FriendlyOlderWomanTwenty-five years ago, my aunt and uncle moved from the Washington, D.C. area to be with my family here on the Great Plains. One of the few complaints that I heard from my aunt about the move was that when she went to their new bank, the tellers called her by her first name. To someone of her generation, a younger person should have been calling her “Mrs. Kelly.” Yes, she understood their intent and she now lived in a more open, friendlier community than before, but she felt that first names lacked dignity. Additionally, while she was obviously aging, her mind was quick and her memory accurate. All she wanted was a little respect.

Read full article on HealthCentral about dignity in names:

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer

Global Alzheimer’s Study Now Enrolling


Don’t Judge a Book by Its Cover: Aging Bodies Often House Strong Minds

ElderlyManCaneAdult children are right to be aware of their parents’ physical and mental changes since there’s no way to stop the aging process. However, as a columnist on caregiving and a forum moderator, I’m seeing something very scary happening far too often. Ageism is overtaking common sense and respect.

The fact that someone is over 65, and perhaps has arthritis and controlled high blood pressure, does not make this person cognitively unstable. Dementia doesn’t necessarily step in even after – gasp! – age 70!

Read more on HealthCentral about ageism and how aging bodies can house strong minds:

Support a caregiver or jump start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol

Global Alzheimer’s Study Now Enrolling


Will Mental Enrichment Delay Alzheimer's?

REadingFor years researchers have tried to understand the impact and significance of a person's education level on the development of Alzheimer's disease. Many studies have shown that people who often challenge themselves to learn complex tasks will show Alzheimer’s symptoms later than those who don’t. Scientists theorized that people who work to enrich their minds, whether through formal means or through a mentally challenging lifestyle, have more cognitive resources at their disposal to mask symptoms of AD.

Read full article on mental enrichment and delaying Alzheimer's:

Support a caregiver or jump start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol

Global Alzheimer’s Study Now Enrolling


Is It a Good Idea to Quit Your Job to Care for Your Elderly Parent?

WomenOldYoungYou already know what may be gained by giving up employment and becoming the sole caregiver for your parents. You are the hands-on person and know their care intimately. You know how they are doing day and night and you hope they will appreciate your help. They raised you and you want to give back. You also could save the money that would be spent for in-home care or adult day care, plus you likely put off, if not eliminate, the need for nursing home care. Therefore, quitting a job and staying home to care for your aging parents could save them significant money. What do you lose if you quit your job to provide care for your parents?

Read more on Agingcare about quitting a job to care for your parents:

Global Alzheimer’s Study Now Enrolling

Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback or ebook

“I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”  Craig William Dayton, Film Composer


What’s Developing in Alzheimer’s Disease Treatment

 By Lawrence Friedhoff, MD, PhD


Lawrence_FriedhoffMy work in Alzheimer’s disease therapeutics began about 20 years ago. After completing my medical training, I was interested to explore another side of medicine—how new drugs are developed.

Attitudes toward dementia have changed drastically over the past two decades. Back then, the term Alzheimer’s disease wasn’t widely used, nor was Alzheimer's disease seen as a credible illness. Instead, people referred to the symptoms of Alzheimer’s disease as "senile dementia,” an inevitable consequence of aging that was considered untreatable.

In the early 90’s, I began working for a mid-size pharmaceutical company, and was placed in charge of finding promising new drugs to bring to market. In looking through many drug candidates and speaking with the scientists who had invented them, I came across a molecule, “E2020,” that I suspected would be an effective treatment for Alzheimer’s disease. I was able to obtain some development budget for E2020, and worked with a small team to get the molecule worldwide drug approval. About 5 years later, that drug became available to patients as Aricept (donepezil), which was then, and is still, the most widely used Alzheimer’s disease treatment.

Scientific and public attitudes about Alzheimer's disease changed with the approval of Aricept and subsequent medications: doctors became more educated about the disease and its diagnosis, and patients and their caregivers became more optimistic about the development of even better treatments.

The medical and scientific communities want to answer that call. Recently, there has been a push to explore medicines targeting a particular protein, beta amyloid, which tends to accumulate in the brain as we age, and is associated with dementia. The hope that these beta amyloid-targeted products could cure Alzheimer's disease meant an enormous amount of time and money was put into their development. Unfortunately, thus far, these investigational drugs have not yet shown any convincing benefit to patients with Alzheimer’s disease.

Although scientists are still pursuing new beta amyloid treatments, I believe the scientific community is turning its attention back to neurotransmitter-targeted drugs, which, like Aricept, act on essential chemicals within the brain in order to augment the brain’s normal functions. I’m currently leading the development of one such drug, called RVT-101, which has strong evidence of benefit to mild-to-moderate Alzheimer’s patients’ cognition and ability to perform daily living activities.

RVT-101 appears to be very well tolerated and is an oral, once-daily pill, so it’s easy for patients to take. Based on the results obtained to date, we believe RVT-101 has a good chance of becoming a widely-used drug for treatment of Alzheimer’s disease and other dementias. We are currently enrolling patients in a Phase III clinical trial of RVT-101, and we think it will be the final trial needed in order to get FDA approval and make the drug available to all patients. Until then, all patients who enroll in and complete our large clinical trial will have the opportunity to receive RVT-101 for up to one full year.

It's important to understand that clinical trials are a fundamental part of getting new treatments to patients, and are especially important for Alzheimer's disease drugs. Tests of Alzheimer's disease treatments in animals have not been predictive of the results in human patients except in a few rare cases. Furthermore, clinical trials can provide benefit to both the patient and future generations: they provide patients an opportunity to get a new drug earlier than would otherwise be possible, and participants may contribute to the advancement of drugs that help other patients. As Alzheimer’s disease occurs more frequently in women than in men, women’s participation in clinical research is particularly important.

However, patients should remember that there is no guarantee that the investigational drug in a clinical trial will ultimately prove to be beneficial— and all drugs have side effects. If clinical trials interest you or a loved one, make sure to discuss participation with your doctor and the staff running the clinical trial in order to determine which clinical trial, if any, is right.

BIO:

Dr. Friedhoff's career in pharmaceutical R&D has spanned more than three decades. During this time he has led and managed teams that developed and obtained approval for six new drugs, including Aricept® (donepezil), the most widely used drug for the treatment of Alzheimer's disease. Dr. Friedhoff is the Chief Development Officer at Axovant Sciences, Inc., a biopharmaceutical company focused on dementia solutions. He is the author of "New Drugs: An Insider's Guide to the FDA Approval Process for Scientists, Investors, and Patients" and has authored and co-authored numerous articles for peer-reviewed publications. He holds an MD from New York University, a PhD in Chemistry from Columbia University, and is a Fellow of the American College of Physicians.

The MINDSET Study for Mild-to-Moderate Alzheimer’s Is Open for Enrollment! 

As a participant in the MINDSET study, Alzheimer’s patients and their caregivers can have access to study-related medical care from specialized teams in this field.  Participants can continue to see their regular doctor(s) while participating in this study, and medical insurance is not required to participate. 

Interested patients and caregivers are invited to visit www.AlzheimersGlobalStudy.com to see if they may pre-qualify.